Table 2 Fat fraction and cross-sectional area of the sciatic nerve compared between Charcot-Marie-Tooth disease type 1A (CMT1A) patients and healthy volunteers.

From: Intraepineurial fat quantification and cross-sectional area analysis of the sciatic nerve using MRI in Charcot-Marie-Tooth disease type 1A patients

Parameter

Level

Estimated difference*

Standard error

p value

FF**

1

ā€‰āˆ’ā€‰0.1618

0.2259

0.4755

2

0.1083

0.2582

0.6757

3

0.6127

0.2630

0.0217ā€ 

CSA**

1

2.5225

0.3148

ā€‰<ā€‰0.0001ā€ 

2

2.7477

0.4000

ā€‰<ā€‰0.0001ā€ 

3

3.2614

0.4494

ā€‰<ā€‰0.0001ā€ 

  1. Analyzed using linear mixed model: group (CMT1A patients, healthy volunteers, sides [L/R]) and reviewers are treated as fixed effects, and subjects are considered as random effects.
  2. FF fat fraction of the sciatic nerve, CSA cross-sectional area of the sciatic nerve.
  3. *Volunteer group used as reference.
  4. **Square root transformations were performed prior to statistical comparison.
  5. ā€ Indicates statistical significance.
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