Table 3 Comparisons of fat fraction and cross-sectional area at different level among Charcot-Marie-Tooth disease type 1A patients and healthy volunteers.

From: Intraepineurial fat quantification and cross-sectional area analysis of the sciatic nerve using MRI in Charcot-Marie-Tooth disease type 1A patients

Group

Comparison

Fat fraction

Cross-sectional area

Estimate

Standard error

p value

Estimate

Standard error

p value

CMT1A patients

Level 1 vs. 2†

4.3676

1.4212

0.0064§

9.1118

2.5669

0.0012§

Level 1 vs. 3†

6.9519

1.4818

 < 0.0001§

3.2417

3.7392

1.0000

Level 2 vs. 3—

2.5843

1.6987

0.3845

āˆ’ 5.8701

3.2702

0.2179

Volunteers

Level 1 vs. 2†

1.8128

1.3758

0.5629

3.9542

2.5211

0.3504

Level 1 vs. 3†

āˆ’ 0.6057

1.7962

1.0000

āˆ’ 4.8453

1.6050

0.0076§

Level 2 vs. 3—

āˆ’ 2.4185

1.8185

0.5506

āˆ’ 8.7994

2.1882

0.0002§

  1. Analyzed using generalized estimating equation with adjustment for sides (L/R) and reviewers.
  2. *Corrected with Bonferroni method due to multiple comparisons.
  3. †Level 1 used as reference.
  4. —Level 2 used as reference.
  5. §Indicates statistical significance.