Table 1 Comparisons of the demographic and clinical characteristics among the NAION, NTG, and healthy control eyes.
NAION group | NTG group | Healthy group | p value | p value | |
---|---|---|---|---|---|
NAION versus NTG group | NAION versus healthy group | ||||
Number of eyes | 27 | 27 | 27 | ||
Sex (male/female) | 16/11 | 10/17 | 11/16 | 0.102 | 0.174 |
Age (years) | 65.2 ± 7.8 | 61.7 ± 11.1 | 61.6 ± 7.1 | 0.182 | 0.079 |
Refractive error (D) | − 0.16 ± 1.73 | − 1.13 ± 2.61 | − 0.66 ± 1.59 | 0.117 | 0.275 |
Intraocular pressure (mmHg) | 15.6 ± 3.2 | 14.9 ± 4.8 | 14.5 ± 2.5 | 0.547 | 0.171 |
Hypertension (n, %) | 5 (18.5%) | 3 (11.1%) | 0.444 | ||
Diabetes (n, %) | 3 (11.1%) | 2 (7.4%) | 0.639 | ||
Hyperlipidemia (n, %) | 2 (7.4%) | 4 (14,8%) | 0.386 | ||
Visual field mean deviation (dB) | − 15.13 ± 8.34 | − 15.11 ± 7.57 | − 0.08 ± 1.47 | 0.991 | < 0.001 |
Cup-to-disc ratio | 0.57 ± 0.17 | 0.78 ± 0.07 | 0.59 ± 0.11 | < 0.001 | 0.546 |
Peripapillary RNFL thickness (μm)\ | 68.6 ± 11.2 | 67.4 ± 12.1 | 89.5 ± 8.5 | 0.700 | < 0.001 |
Peripapillary vessel density (%) | 32.1 ± 7.4 | 38.1 ± 7.9 | 59.4 ± 3.5 | 0.006 | < 0.001 |
Choroidal vessel density of β-PPA (%) | 49.9 ± 5.2 | 50.0 ± 5.2 | 59.7 ± 3.2 | 0.949 | < 0.001 |
β-PPA area (mm2) | 1.166 ± 0.410 | 1.215 ± 0.566 | 1.369 ± 0.414 | 0.735 | 0.089 |
Presence of CMvD (n, %) | 15 (55.6) | 20 (74.1) | 0 | 0.154 | |
CMvD area (mm2) | 0.278 ± 0.172 | 0.138 ± 0.068 | 0.002 | ||
CMvD angular width (°) | 86.5 ± 42.3 | 35.1 ± 16.2 | < 0.001 |