Figure 4
From: Tissue, age, sex, and disease patterns of matrisome expression in GTEx transcriptome data
Commonly upregulated and downregulated matrisome gene transcripts. (a) A histogram of transcript rank changes between combined TCGA normal samples (n = 110) and GTEx samples (n = 374) compared to TCGA cancer samples (n = 542) in lung. The histogram is colored on the decile of rank change. (b) A histogram of the sum of normal to cancer rank changes for gene transcripts across lung, breast, colon thyroid and prostate (n = 443). The histogram is colored on the decile of rank change. (c) A heatmap of the top and bottom rank-changed matrisome gene transcripts between normal tissue and cancer. The rank change order is split into deciles, (1—1st decile to 10—10th decile). NAs are represented by black boxes and indicate no expression in the normal or cancer samples.
