Figure 5
From: Tissue, age, sex, and disease patterns of matrisome expression in GTEx transcriptome data
Idiopathic Lung Fibrosis characterization using GTEx. (a) A heat map representing the centered normalized expression of matrisome genes in clusters LUNG-Fib.1 or LUNG-Fib.2 between lung samples. The x-axis of the lung samples indicates disease, batch, tobacco usage, sex, and age status of each. Age and being in batch Sivakumar—2 significantly correlate with IPF samples (logistic regression; p = 0.012; p = 0.029 respectively). (b) A violin-sina plot of the normalized score of gene expression cluster LUNG-Fib.1 and LUNG-Fib.2 comparing IPF, acute lung injury, ventilator injury, and normal lung samples from Sivakumar et al. The color of each data point indicates the batch.
