Figure 7 | Scientific Reports

Figure 7

From: RETRACTED ARTICLE: Eupafolin induces apoptosis and autophagy of breast cancer cells through PI3K/AKT, MAPKs and NF-κB signaling pathways

Figure 7

Eupafolin inhibited the oncogenic capability of MCF-7 cells in nude mouse xenografts. (A) Nude mice bearing MCF-7 tumor xenografts were treated with Eupafolin (50 mg/kg, once daily, intraperitoneal injection). (B) Body weight of nude mice. (C) Schematic diagram of the potential molecular mechanism of Eupafolin-induced anticancer effect. The interaction between Eupafolin and PI3K/AKT, MAPKs and NF-κB is demonstrated. Data are representative of three independent experiments and expressed as mean ± SD. P > 0.05 indicates non-significance; ***P < 0.001; **P < 0.01; *P < 0.05.

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