Figure 1
From: Expression of truncated Kir6.2 promotes insertion of functionally inverted ATP-sensitive K+ channels
Schematic diagram of Kir6.2 variants. Illustration shows the Kir6.2 constructs used with the N- and C-termini deleted and/or fused with 6xHis and EGFP. Full length wild-type Kir6.2 contains 390 amino acids with two transmembrane segments (M1 and M2) and a pore-forming H5 segment (i). C-terminal truncated Kir6.2, Kir6.2ΔC26 (ii), N-terminal 6xHis tag fused with Kir6.2ΔC26, 6xHis-Kir6.2ΔC26 (iii), and 6xHis and EGFP chimera N-terminal fused with Kir6.2ΔC26, 6xHis-EGFP-Kir6.2ΔC26 (iv).
