Table 1 Variations of fabrication techniques developed for the manufacturing of μPADs.

From: The pursuit of further miniaturization of screen printed micro paper-based analytical devices utilizing controlled penetration towards optimized channel patterning

Fabrication method

Hydrophobic agent

Achieved resolution

Paper type

References

Laser treatment

Silicone coating

62 ± 1 μm

Parchment paper

10

Pen plotting

Hydrophobic ink

150 ± 12 μm

Whatman No. 1

11

Photolithography

SU-8

186 ± 13 μm

Chromatography paper

9

Screen-printing

Rubber latex

256 ± 21 μm

Paper towel

25

540 ± 70 μm

Whatman No. 4

780 ± 98.5 μm

Whatman No. 1

Varnishing paint

500 μm

28

PDMS

650 μm

26

Wax

650 ± 71 μm

21

Polystyrene

671 ± 51 μm

Whatman No. 4

29

PMMA

1000 μm

27

Inkjet printing

UV curable acrylate ink

272 ± 19 μm

Advantec No. 5C

16

Chemical treatment

Wax (μPAD submerged in NaIO4)

301 μm

Whatman No. 1

19

Flexography printing

Hydrophobic ink

500 μm

20

Inkjet etching

Polystyrene

550 μm

Advantec No. 2

17

Wax dipping

Wax

639 ± 7 μm

Whatman No. 1

18

3D pen drawing

Acrylic resin

2000 μm

Whatman No. 1

30

UV light curing

Water-based polyurethane acrylate

200 μm

Whatman No. 1

31