Figure 2
A typical example of 2D and 3D DWI IVIM analysis in a hepatocellular carcinoma at 1.5 T. Original diffusion-weighted images with b = 0, 50, 250, 800 s/mm2 are presented together with conventional ADC maps displayed as color-coded overlays over b800 images. For analysis, on each tumor-containing slice a region of interest (ROI) was selected, where ADC and IVIM parameters (not shown) were analyzed. ADC values are given in units of 10−6 mm2/s. Slices largely unaffected by artifacts were defined as good (“G”), slices close to the lesion’s rim (partial volume) or with images affected by artifacts (see red x) due to motion, susceptibility or pixel misalignments were defined as bad (“B”). One central “good” slice served as reference (“REF”) for the 2D analysis (see green frame), hereby slices in the lower part of the liver should be preferred due to lower motion influences from the heart. For 3D analysis, the voxels of the 2D ROI were combined with voxels of the ROIs on other “good” slices (3DG), voxels of all ROIs was used for whole lesion analysis (3DA).
