Figure 8
From: Functional roles of the membrane-associated AAV protein MAAP
MAAP effects on capsid levels. Plasmids with wt-AAV2 or AAV2 encoding MAAP variants were co-transfected with Ad helper plasmid. From cell extracts harvested 72 hpt, we performed AAV2 capsids ELISA (A), expressed as AAV capsids per mL with mean and the standard deviation (SD). Statistical significance between wt-AAV2 and AAV2 encoding MAAP mutants was evaluated using ANOVA followed by Dunnett’s multiple comparison test. Table (B) indicates the average AAV per mL capsid titer measured for each virus, along with the fold difference compared to wt-AAV2.
