Table 3 Top 10 pathways with significant enrichment of differentially expressed genes (in order of increasing p-value).
From: Bioinformatic analysis of the gene expression profile in muscle atrophy after spinal cord injury
Pathway ID | Pathway name | P value | FDR | Gene symbols | Rank |
|---|---|---|---|---|---|
1100 | Metabolic pathways | 2.56E−17 | 5.19E−15 | |Ndufv3|Acaca|Mthfd2l|Acot1|Nnt|Acox2|Flad1|Idh1|LOC100359539|LOC691853|Fahd1|Acsl1|Hadh|St3gal6|Acadvl|Cat|Mdh1|Mgll|Ndufs1|Pmvk|Ak4|Acat1|Ldha|LOC497978|Acsl4|Coq5|Bdh1|Synj2|Pgp|Cda|Acot7|Impa2|Odc1|Pccb|Hyal3|Ugp2|Inpp5a|Acot2|Hpd|Alox15|Echs1|Pank1|Mlycd|Hadha|Pola2|Agpat2|Pla2g12a|Chkb|Ndufa9|Idh2|Pla2g4b|Acaa2|Pigo|Glul|Ppcs|Pla2g16|Acss1|Hadhb|Extl1|Ndufa8| | 1 |
3320 | PPAR signalling pathway | 3.29E−12 | 3.34E−10 | |Sorbs1|Fabp3|Fabp4|Cd36|Acox2|Pparg|Aqp7|Ppara|Acsl1|Rxrg|Adipoq|Cpt1b|Acsl4|Lpl| | 2 |
4146 | Peroxisome | 8.01E−12 | 5.42E−10 | |Acsl4|Idh1|Cat|Mlycd|Ech1|Gstk1|LOC100362572|Acox2|Pmvk|Acsl1|Idh2|Pxmp2|Pex19|Gnpat| | 3 |
71 | Fatty acid degradation | 2.93E−11 | 1.49E−09 | |Acadvl|Cpt1b|Eci1|Acat1|Echs1|Acsl1|Acsl4|Hadhb|Hadh|Hadha|Acaa2| | 4 |
62 | Fatty acid elongation | 2.81E−09 | 1.14E−07 | |Acot7|Acot1|Hadha|Hadh|Hadhb|Acot2|Acaa2|Echs1| | 5 |
480 | Glutathione metabolism | 7.73E−09 | 2.61E−07 | |Mgst3|Gsr|LOC100359539|Gstk1|Idh1|Odc1|Gstm5|Gsta3|Ggct|Idh2| | 6 |
640 | Propanoate metabolism | 1.64E−08 | 4.76E−07 | |Acss1|Mlycd|Echs1|Ldha|Acaca|Pccb|Hadha|Acat1| | 7 |
280 | Valine, leucine, and isoleucine degradation | 7.16E−07 | 1.82E−05 | |Pccb|Oxct1|Hadhb|Hadh|Acat1|Hadha|Acaa2|Echs1| | 8 |
4920 | Adipocytokine signalling pathway | 9.37E−07 | 2.11E−05 | |Cpt1b|Adipoq|Jak2|Irs2|Ppara|Cd36|Rxrg|Acsl4|Acsl1| | 9 |
630 | Glyoxylate and dicarboxylate metabolism | 1.05E-06 | 2.13E-05 | |Glul|Pgp|Mdh1|Cat|Acat1|Pccb| | 10 |
