Table 5 Top 10 hub genes from gene signal network analysis based on betweenness (in order of decreasing betweenness-value).

From: Bioinformatic analysis of the gene expression profile in muscle atrophy after spinal cord injury

Gene symbol

Gene feature

Gene description

Betweenness

Indegree

Outdegree

Degree

Rank

Acat1

Down

Acetyl-CoA acetyltransferase 1

125.4286

8

8

16

1

Acadvl

Down

Acyl-CoA dehydrogenase, very long chain

123.4

7

7

14

2

Acaa2

Down

Acetyl-CoA acyltransferase 2

41.6024

5

5

10

3

Hadhb

Down

Hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit

41.6024

5

5

10

4

Acss1

Down

Acyl-CoA synthetase short-chain family member 1

39.1333

4

4

8

5

Oxct1

Down

3-Oxoacid CoA transferase 1

34

3

3

6

6

Hadha

Down

Hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit

33.669

6

6

12

7

Hadh

Down

Hydroxyacyl-CoA dehydrogenase

32.0714

6

6

12

8

Acaca

Down

Acetyl-CoA carboxylase alpha

16

3

2

5

9

Cpt1b

Down

Carnitine palmitoyltransferase 1b, muscle

15

6

3

9

10