Table 5 Top 10 hub genes from gene signal network analysis based on betweenness (in order of decreasing betweenness-value).
From: Bioinformatic analysis of the gene expression profile in muscle atrophy after spinal cord injury
Gene symbol | Gene feature | Gene description | Betweenness | Indegree | Outdegree | Degree | Rank |
|---|---|---|---|---|---|---|---|
Acat1 | Down | Acetyl-CoA acetyltransferase 1 | 125.4286 | 8 | 8 | 16 | 1 |
Acadvl | Down | Acyl-CoA dehydrogenase, very long chain | 123.4 | 7 | 7 | 14 | 2 |
Acaa2 | Down | Acetyl-CoA acyltransferase 2 | 41.6024 | 5 | 5 | 10 | 3 |
Hadhb | Down | Hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit | 41.6024 | 5 | 5 | 10 | 4 |
Acss1 | Down | Acyl-CoA synthetase short-chain family member 1 | 39.1333 | 4 | 4 | 8 | 5 |
Oxct1 | Down | 3-Oxoacid CoA transferase 1 | 34 | 3 | 3 | 6 | 6 |
Hadha | Down | Hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), alpha subunit | 33.669 | 6 | 6 | 12 | 7 |
Hadh | Down | Hydroxyacyl-CoA dehydrogenase | 32.0714 | 6 | 6 | 12 | 8 |
Acaca | Down | Acetyl-CoA carboxylase alpha | 16 | 3 | 2 | 5 | 9 |
Cpt1b | Down | Carnitine palmitoyltransferase 1b, muscle | 15 | 6 | 3 | 9 | 10 |