Table 3 Variation in median nevirapine and efavirenz plasma concentration and HIV stigma, disclosure and social support-related variables.
Variable | NEVIRAPINE (N = 254) | EFAVIRENZ (N = 312) | ||||||||
---|---|---|---|---|---|---|---|---|---|---|
n | Median | (IQR) | P | n | Median | (IQR) | P | |||
Age group (Years) | ||||||||||
20–30 | 25 | 6034 | 4448 | 7817 | 41 | 2961 | 1679 | 4603 | ||
31–40 | 84 | 6207 | 4558 | 8946.5 | 0.667 | 126 | 2698.5 | 1918 | 5976 | 0.476 |
41–50 | 106 | 6368 | 4599 | 9784 | 96 | 2685.5 | 1950.5 | 4282.5 | ||
> 51 | 39 | 6011 | 4518 | 8843 | 49 | 2754 | 1833 | 4074 | ||
Gender | ||||||||||
Male | 91 | 5917 | 4449 | 8638 | 0.387 | 133 | 2747 | 1918 | 5336 | 0.728 |
Female | 163 | 6364 | 4558 | 9293 | 179 | 2712 | 1868 | 4647 | ||
HIV drug resistant mutation | ||||||||||
Yes | 24 | 6062 | 4119 | 8786 | 0.519 | 10 | 1373.5 | 49 | 2807 | 0.006 |
No | 230 | 6237.5 | 4532 | 9163 | 302 | 2758.5 | 1918 | 5139 | ||
HIV viral load (Cells/mls) | ||||||||||
< 1000 | 230 | 6237.5 | 4532 | 9095 | 0.609 | 300 | 2764 | 1919.5 | 5171.5 | 0.002 |
≥ 1001 | 24 | 6062 | 4119 | 8866 | 12 | 1373.5 | 52.5 | 2714 | ||
Current ART regimen | ||||||||||
3TC, ABC | 1 | 8798 | 8798 | 8798 | 1 | 1434 | 1434 | 1434 | ||
3TC, TDF | 159 | 6698 | 4599 | 9755 | 0.2481 | 187 | 2621 | 1838 | 5139 | 0.3519 |
3TC, ZDV | 93 | 5729 | 4448 | 8323 | 124 | 2796.5 | 1968 | 4726.5 | ||
3TC, d4T | 1 | 3552 | 3552 | 3552 | ||||||
Being HIV positive makes me feel guilty | ||||||||||
Agree | 81 | 5557 | 4247 | 7633 | 0.016 | 108 | 2645.5 | 1895 | 5171.5 | 0.927 |
Disagree | 173 | 6511 | 4607 | 9863 | 204 | 2854 | 1869 | 4839.5 | ||
Being HIV positive makes me feel it worthless | ||||||||||
Agree | 55 | 5243 | 3975 | 7311 | 0.054 | 82 | 2756 | 1951 | 4319 | 0.837 |
Disagree | 199 | 6511 | 4599 | 9755 | 230 | 2720.5 | 1838 | 5204 | ||
Disclosed HIV status to partner or spouse | ||||||||||
Yes | 204 | 6402.5 | 4564.5 | 9180.5 | 242 | 2759.5 | 1886 | 5204 | ||
No | 25 | 4853 | 3450 | 6202 | 0.036 | 38 | 2991 | 1918 | 5336 | 0.565 |
Not applicable | 25 | 6273 | 4577 | 9909 | 32 | 2556 | 1750 | 3488 | ||
Disclosed HIV status to family members | ||||||||||
Yes | 166 | 5967.5 | 4444 | 7966 | 183 | 2592 | 1917 | 5044 | ||
No | 87 | 6868 | 4951 | 10,635 | 0.064 | 125 | 2867 | 1870 | 4911 | 0.312 |
Not applicable | 1 | 8034 | 8034 | 8034 | 4 | 1699.5 | 456.5 | 3118.5 | ||
Disclosed HIV status to neighbor | ||||||||||
Yes | 13 | 5239 | 3631 | 7009 | 22 | 3079 | 1917 | 7572 | ||
No | 234 | 6237.5 | 4558 | 9095 | 0.210 | 280 | 2739.5 | 1902 | 4837 | 0.088 |
Not applicable | 7 | 7966 | 6372 | 9909 | 10 | 2027.5 | 857 | 2961 | ||
Disclosed HIV status to religious leaders | ||||||||||
Yes | 18 | 4479 | 2960 | 7009 | 26 | 2440 | 1633 | 5909 | ||
No | 222 | 6317 | 4607 | 9293 | 0.055 | 264 | 2821.5 | 1945 | 5270 | 0.003 |
Not applicable | 14 | 6371.5 | 4211 | 8034 | 22 | 1998.5 | 1548 | 2520 | ||
Disclosed HIV status to public | ||||||||||
Yes | 5 | 5736 | 5239 | 7009 | 7 | 3097 | 2872 | 5976 | ||
No | 231 | 6202 | 4503 | 9163 | 0.869 | 282 | 2766.5 | 1918 | 5139 | 0.012 |
Not applicable | 18 | 6595.5 | 4558 | 8034 | 23 | 1965 | 1639 | 2763 | ||
Get financial help during emergency | ||||||||||
As much as I wouild like | 162 | 6365.5 | 4558 | 8964 | 175 | 2836 | 1918 | 4911 | ||
Less than I wouild like | 40 | 5468.5 | 4275 | 8191.5 | 0.492 | 52 | 2309.5 | 1789.5 | 5038 | 0.797 |
Much less than I wouild like | 12 | 7275.5 | 6056.5 | 9583 | 32 | 2747.5 | 1615.5 | 8797.5 | ||
Never | 40 | 5710.5 | 4046 | 9867.5 | 53 | 2872 | 2043 | 4241 | ||
Get transportation help when needed | ||||||||||
As much as I wouild like | 169 | 6538 | 4571 | 9198 | 188 | 2821.5 | 1895 | 5223.5 | ||
Less than I wouild like | 38 | 5527.5 | 4336 | 8382 | 0.550 | 43 | 2462 | 1818 | 4872 | 0.917 |
Much less than I wouild like | 15 | 6202 | 4180 | 6868 | 30 | 2670 | 1679 | 6875 | ||
Never | 32 | 5635.5 | 3955.5 | 8750 | 51 | 2786 | 1942 | 3875 | ||
Get general help when sick | ||||||||||
As much as I wouild like | 212 | 6351 | 4448.5 | 9129 | 244 | 2796.5 | 1895 | 4977.5 | ||
Less than I wouild like | 27 | 5911 | 4990 | 9411 | 0.970 | 40 | 2569 | 1999.5 | 5589.5 | 0.534 |
Much less than I wouild like | 6 | 7039 | 5729 | 8405 | 12 | 2447.5 | 911 | 4693 | ||
Never | 9 | 5692 | 5457 | 7009 | 16 | 2931.5 | 1613.5 | 4168 |