Table 4 Regression analysis between nevirapine and efavirenz plasma concentrations and HIV stigma variables.

From: Association between social psychological status and efavirenz and nevirapine plasma concentration among HIV patients in Kenya

Variable

NEVIRAPINE (N = 254)

EFAVIRENZ (N = 312)

Unadjusted β

(95% CI)

p value

Unadjusted β

(95% CI)

p value

Age

− 14

− 56.2

28.2

0.307

− 13.7

− 38.7

11.4

0.284

Gender

447

− 545.5

1439.5

0.376

− 35

− 536.5

466.5

0.891

Alcohol use number of times

− 198

− 680.7

284.7

0.42

330

− 534.4

1194.4

0.453

Age of sexual debut

− 364

− 1385.8

657.8

0.484

54

− 459.7

567.7

0.836

Number of sexual life partners

− 600

− 1285.7

85.7

0.086

− 557

− 918.0

− 196.0

0.003

Number of sexual acts in the past 3 months

− 46.5

− 748.9

655.9

0.896

− 106

− 648.9

436.9

0.701

Presence of HIV drug resistant mutation

− 117

− 2064.4

1830.4

0.906

1388

484.1

2291.9

0.003

Viral load (Cells/mls)

117

− 2474

2708

0.929

− 1390

− 2642.7

− 137.3

0.03

Difficult to tell others about my HIV infection

141

− 958.8

1240.8

0.801

− 126

− 703.9

451.9

0.668

Being HIV positive makes me feel guilty

954

26.7

1881.3

0.044

210

− 281.3

701.3

0.401

Being HIV positive makes me feel it worthless

1268

379.4

2156.6

0.005

− 33

-744.7

678.7

0.927

Feel certain to tell primary sexual partner being HIV positive

372

− 453.2

1197.2

0.376

426

24.3

827.7

0.038

Disclose HIV status to anyone

− 539

− 1578.8

500.8

0.308

983

− 1058.0

3024.0

0.344

Disclosed HIV status to family members

1051.5

− 541.5

2644.5

0.195

134

− 381.8

649.8

0.61

Disclosed HIV status to neighbor

1675

137.5

3212.5

0.033

− 445

− 1441.0

551.0

0.38

Disclosed HIV status to employers

− 112

− 1203.3

979.3

0.84

− 489

− 1037.2

59.2

0.08

Disclosed HIV status to religious leaders

1609

− 98.7

3316.7

0.065

− 410

− 907.9

87.9

0.106

Get useful advice about importat things in life

− 539

− 1778.4

1303.7

0.762

− 134.3

− 483.8

215.1

0.45

Get financial help during emergency

− 124.7

− 541.9

292.6

0.557

18.7

− 189.8

227.1

0.86

Get transportation help when needed

− 300

− 512.1

− 87.9

0.006

− 5

− 177.6

167.6

0.955

Get general help when sick

− 217

− 599.7

165.7

0.265

− 158

− 562.3

246.3

0.442

Variable

NEVIRAPINE (N = 254)

EFAVIRENZ (N = 312)

Adjusted β

(95% CI)

p value

Adjusted β

(95% CI)

p value

Age

0.421

− 71.7

72.5

0.991

− 15.5

− 52.5

21.6

0.412

Gender

172

− 1010.5

1354.5

0.775

− 40.4

− 832.7

751.9

0.92

Alcohol use number of times

− 162.5

− 811

486

0.622

398

− 431.2

1227.2

0.346

Age of sexual debut

− 1008.1

− 2745.4

729.1

0.254

563.5

− 424.6

1551.6

0.263

Number of sexual life partners

− 988

− 2156.8

180.8

0.097

− 845.7

− 1315.0

− 376.4

0.0001

Number of sexual acts in the past 3 months

− 2180.8

− 5358.2

996.6

0.178

487.3

− 3224.2

4198.8

0.796

Presence of HIV drug resistant mutation

226.1

− 7513.4

7965.6

0.954

− 1192.0

− 5251.2

2867.2

0.564

Viral load (Cells/mls)

559.9

− 6645.1

7764.9

0.878

0.0

0.0

0.1

0.339

Difficult to tell others about my HIV infection

− 528.5

− 1633.9

576.9

0.347

− 177

− 1021.3

667.3

0.68

Being HIV positve makes me feel guilty

954

192.7

1715.3

0.014

347.7

− 153.4

848.7

0.173

Being HIV positve makes me feel it worthless

852

64.3

1639.7

0.034

− 143.3

− 759.2

472.5

0.647

Feel certain to tell primary sexual partner being HIV positive

341.5

− 1357.0

2040.0

0.692

363

97.9

628.1

0.007

Disclose HIV status to anyone

− 1042.9

− 2597.4

511.6

0.188

1342

1653.6

4337.6

0.379

Disclosed HIV status to family members

812.9

− 483.3

2109.1

0.218

245

− 365.8

855.8

0.431

Disclosed HIV status to neighbor

1731

376.0

3086.0

0.012

− 251

− 1714.1

1212.1

0.736

Disclosed HIV status to employers

− 393.5

− 1586.1

799.1

0.516

− 505

− 1410.3

400.3

0.273

Disclosed HIV status to religious leaders

241.6

− 1675.6

2158.7

0.804

29

− 1120.3

1178.3

0.96

Get useful advice about importat things in life

− 112.7

− 1430.0

1204.6

0.866

16.4

− 400.5

433.4

0.938

Help with household duties

− 315.2

− 1460.0

829.6

0.588

− 226.4

− 556.1

103.4

0.178

Get financial help during emergency

779.3

− 291.9

1850.6

0.153

245.0

− 304.7

794.7

0.381

Get transportation help when needed

− 1143.3

− 1914.3

− 372.4

0.004

− 6.6

− 377.8

364.7

0.972

Get general help when sick

212.3

− 560.5

985.1

0.589

74.1

− 478.3

626.5

0.792