Figure 2 | Scientific Reports

Figure 2

From: Neurofilaments can differentiate ALS subgroups and ALS from common diagnostic mimics

Figure 2

Neurofilament levels and ROC analyses. (A) Boxplots of CSF NFL concentration estimates of participants in the ALS, ALS mimics and control groups. (B) ROC analysis of participants in the ALS versus ALS mimics groups for CSF NFL. (C) Boxplots of CSF pNFH concentration estimates in participants in the ALS, ALS mimics and control groups. (D) ROC analysis of participants in the ALS versus ALS mimics groups for CSF pNFH. (E) Boxplots of plasma NFL concentration estimates of participants in the ALS, ALS mimics and control groups. (F) ROC analysis of participants in the ALS versus ALS mimics groups for plasma NFL. ALS patients versus participants with other MNDs, participants with neuropathies & myelopathies, participants with myopathies and controls: *p < 0.05, **p < 0.01, ns  non-significant. Participants with other MNDs versus participants with neuropathies & myelopathies, participants with myopathies and controls: #p < 0.05, ##p < 0.01.

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