Figure 6
From: Methylation profiling reveals novel molecular classes of rhabdomyosarcoma
Suggested molecular re-classification of RMS and Clinical Outcome. The histologic type designated at diagnosis was compared to the molecular classification by methylation profiling and displayed as a Sankey diagram (A). Methylation profiling was able to classify a significant number of tumors that could not be classified using traditional histology. Clinical outcome data in the Kaplan–Meier plot (B) highlights poor outcome in the pleomorphic, alveolar, and spindle/sclerosing groups. Numerical data (C) displaying number at risk over a ten year period.
