Table 3 Correspondence analysis. Introducing the key residues in each domain.
From: Hotspots for mutations in the SARS-CoV-2 spike glycoprotein: a correspondence analysis
Domain (total number of nonredundant sequences) | Association | Secondary content | Occurrence | Sequences |
|---|---|---|---|---|
16–305 NTD (85) | F32, T33 | Coil | Once, 1.18% | A0A0U1WJY8 (BtRs-BetaCoV/YN2013), A0A1W5YKT9 (Bat coronavirus, UC) |
330–521 RBD (230) | T500, N501 | Coil, Coil | 39 (45.88), 6 (7.06) | – |
522–907 (1898) | NA |  |  |  |
660–700 (Furin cleavage motif: 194) | Q675, Q677, T678, A684 | Coil, Coil, Coil, Extended strand | Once (0.52%) | – |
908–985 HR1 (937) | NA |  |  |  |
986–1035 CH (344) | E990, | Helix | 6 (1.74%) | A0A0P0INJ4 (SARS-like coronavirus BatCoV/BB9904/BGR/2008), D2DJW4 (SARS coronavirus Rs_672/2006), A0A0U1WHK9 (BtRf-BetaCoV/HeN2013), Q6R7Y6 (SARS coronavirus NS-1) |
1076–1141 CD (34) | NA |  |  |  |
