Table 3 Uni- and multi-variable analysis for risk factors of invasive fungal infection.
Characteristics | IFI episodes (n = 40) | Non-IFI episodes (n = 512) | Univariable analysis | Multivariable analysis | |
|---|---|---|---|---|---|
P | aOR (95% CI) | P | |||
Age, median (IQR) | 58 (41–65) | 54 (43–62) | 0.052 | 1.01 (0.96–1.06) | 0.768 |
Male | 15 (37.5) | 263 (51.4) | 0.091 | 0.69 (0.28–1.70) | 0.422 |
CCI score, median (IQR) | 3 (2–5) | 3 (2–4) | 0.136 | 1.05 (0.74–1.48) | 0.805 |
AML (vs. ALL) | 28 (70.0) | 365 (71.3) | 0.862 | 1.30 (0.32–5.19) | 0.714 |
Induction or re-induction chemotherapy (vs. consolidation) | 29 (72.5) | 281 (54.9) | 0.031 | 1.79 (0.71–4.52) | 0.220 |
No antimold prophylaxis | 27 (67.5) | 294 (57.4) | 0.213 | 3.52 (1.35–9.22) | 0.010 |
Duration of neutropenia, day, median (IQR) | 21 (12–32) | 15 (8–25) | 0.006 | 1.02 (1.01–1.04) | 0.001 |
