Table 2 Main cardiac parameters calculated from magnetic resonance exams performed throughout the study.

From: The epicardial delivery of cardiosphere derived cells or their extracellular vesicles is safe but of limited value in experimental infarction

Groups

CON

EV

CDC

Baseline preinjection

10 weeks

Baseline preinjection

10 weeks

Baseline preinjection

10 weeks

LVEF (%)

27 ± 3

29 ± 7

27 ± 4

29 ± 13

28 ± 5

32 ± 8

EDVi (mL/m2)

93 ± 17

98 ± 19

81 ± 11

97 ± 29

84 ± 9

89 ± 20

ESVi (mL/m2)

68 ± 13

71 ± 19

59 ± 9

71 ± 31

60 ± 8

62 ± 21

Infarct size (%)

25 ± 7

12 ± 3

21 ± 5

10 ± 2

21 ± 3

10 ± 3

Cardiac output (L/min)

1.8 ± 0.3

2.6 ± 0.4

1.3 ± 0.3

2.4 ± 0.9

1.8 ± 0.4

2.8 ± 0.6

Beats per minute

93 ± 12

90 ± 7

86 ± 12

102 ± 17

95 ± 12

95 ± 16

Δ LVEF (%)

n/a

2 ± 7

n/a

2 ± 11

n/a

3 ± 8

Δ EDVi (mL/m2)

n/a

6 ± 24

n/a

16 ± 29

n/a

5 ± 21

Δ ESVi (mL/m2)

n/a

3 ± 21

n/a

12 ± 26

n/a

2 ± 21

Δ Infarct size (%)

n/a

− 13 ± 6

n/a

− 11 ± 4

n/a

− 11 ± 2

  1. Data presented as mean ± standard deviation.
  2. LVEF left ventricular ejection fraction, EDVi end diastolic volume indexed to body surface area, ESVi end systolic volume indexed to body surface area.
  3. Infarct area is expressed as % of the left ventricle. n/a not applicable.
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