Table 9 Concentration and detection rate more than LOQ of urinary neonicotinoids and DMAP (μg/g Cre) in each class of urinary creatinine-adjusted Cystatin-C concentration.

From: Urinary concentrations of neonicotinoid insecticides were related to renal tubular dysfunction and neuropsychological complaints in Dry-zone of Sri Lanka

 

Zero CysC

(A)

Normal CysC

(B)

High CysC

(C)

A vs B

p valuea

B vs C

p valuea

Correlation Coefficientb

Detection rate > LOQ%

DMAP

71.4%

96.2%

85.7%

0.007

0.21

 

Dinotefuran

28.6%

15.4%

28.6%

0.38

0.37

 

Thiamethoxam

42.9%

20.5%

0%

0.17

0.18

 

Imidacloprid

0%

2.6%

14.3%

0.67

0.11

 

Clothianidin

28.6%

16.7%

0%

0.43

0.24

 

Thiacloprid

14.3%

2.6%

0%

0.11

0.67

 

Concentration, uncorrected (mean ± SD, μg/L)

DMAP

1.90 ± 2.31

0.81 ± 0.92

0.58 ± 0.68

0.013, 0.38

0.53, 0.44

 − 0.08, 0.44

Dinotefuran

0.24 ± 0.45

0.07 ± 0.19

0.33 ± 0.63

0.049, 0.28

0.009, 0.25

0.01, 0.92

Thiamethoxam

0.10 ± 0.13

0.21 ± 0.87

0

0.73, 0.26

IC, 0.25

 − 0.04, 0.73

Imidacloprid

0

0.08 ± 0.62

0.01 ± 0.03

IC, 0.67

0.78, 0.12

 − 0.014, 0.89

Clothianidin

0.15 ± 0.31

0.04 ± 0.13

0

0.057, 0.33

IC, 0.25

 − 0.05, 0.64

Thiacloprid

0.04 ± 0.12

0.01 ± 0.04

0

0.035, 0.098

IC, 0.67

 − 0.03, 0.79

Concentration, creatinine corrected (mean ± SD, μg/g Cre)

DMAP

9.20 ± 8.70

1.16 ± 1.98

0.98 ± 1.08

 < 0.001, 0.068

0.82, 0.99

 − 0.06, 0.57

Dinotefuran

2.12 ± 4.32

0.07 ± 0.19

0.42 ± 0.85

 < 0.001, 0.27

0.003, 0.24

 − 0.02, 0.88

Thiamethoxam

0.61 ± 0.98

0.26 ± 0.92

0

0.34, 0.14

IC, 0.25

 − 0.05, 0.65

Imidacloprid

0

0.04 ± 0.24

0.01 ± 0.03

IC, 0.67

0.79, 0.12

 − 0.01, 0.89

Clothianidin

0.63 ± 1.35

0.05 ± 0.15

0

 < 0.001, 0.27

IC. 0.25

 − 0.04, 0.73

Thiacloprid

0.17 ± 0.45

0.004 ± 0.031

0

0.001, 0.098

IC, 0.67

 − 0.02, 0.84

  1. IC: incalculable; aFor > LOQ%, Chi-square test, for neonicotinoids concentration, t test, Mann–Whitney U test (2-tailed); bPearson correlation Coefficient between neonicotinoids/DMAP and Cystatin C in A, B and C, R, p value.