Table 1 Demographic and clinical characteristics.

From: The trajectory of putative astroglial dysfunction in first episode schizophrenia: a longitudinal 7-Tesla MRS study

Characteristic

Patient group (N = 21)

Healthy controls (N = 10)

t/χ2

P

Gender (male/female)

16/5

5/5

2.13

0.145

Marital status (Mar/S)

1/20

1/9

0.31

0.58

Inpatient at baseline (Y/N)

11/10

   

Family Hx (Y/N/DN)

10/6/5

   

AP exposure at baseline (M/SD; days)

2.95/3.11

   

Total DDD-days at baseline scan (M/SD)

2.25/4.74

   

Total DDD-days at FUP scan (M/SD)

145.68/97.56

   

DUP (M/SD/median; weeks)

29.38/26.65/18

   

Ethnicity (Black/White/Other)

2/18/1

0/5/5

4.51

0.034a

Age (M/SD)

22.33/5.29

21.60/3.37

 − 0.47

0.645

SOFAS at baseline scan (M/SD)

42.33/12.84

83.70/5.62

12.47

0.000

SOFAS at FUP scan (M/SD)

61.25/9.85

85.10/3.21

9.83

0.000

PANSS-8 total at baseline scan (M/SD)

24.67/5.30

   

PANSS-8 total at FUP scan (M/SD)

14.35/4.77

   

Smoker (yes/no)

6/15

0/10

3.54

0.060

Cannabis user (yes/no)

13/8

0/10

10.66

0.001

Time between scans (M/SD; months)

5.93/1.25

7.67/1.90

2.63

0.021

  1. Mar married, S single, Y yes, N no, Hx history, DN don’t know, AP antipsychotic, M mean, SD standard deviation, DDD defined daily dose, FUP follow-up, DUP duration untreated psychosis.
  2. P values for differences between groups were calculated using chi-square analyses for categorical variables and independent t tests for continuous variables.
  3. aWhite vs non-White comparison.
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