Table 3 Effects of in utero heat stress (IUHS) and age on the mRNA abundance of hypothalamic–pituitary–adrenal axis associated receptors and hormones in the hypothalamus, anterior pituitary, and adrenal glands of pigs.
Parameter | In utero treatment—age | SEM | P-value | |||||
---|---|---|---|---|---|---|---|---|
IUTN-10-week | IUHS-10-week | IUTN-15-week | IUHS-15-week | IU | A | IU × A | ||
N | 12 | 12 | 12 | 12 | ||||
Hypothalamus | ||||||||
GR | 1.49 | 1.26 | 0.77 | 0.66 | 0.19 | 0.39 | < 0.01 | 0.84 |
CRH | 1.10xy | 0.99xy | 0.89x | 1.31y | 0.21 | 0.32 | 0.90 | 0.09 |
Anterior pituitary | ||||||||
GR | 1.83 | 1.62 | 0.40 | 0.39 | 0.25 | 0.81 | 0.03 | 0.76 |
POMC | 1.26 | 1.20 | 1.02 | 1.15 | 0.23 | 0.87 | 0.47 | 0.64 |
CRHR 1 | 1.05 | 0.68 | 0.94 | 1.07 | 0.36 | 0.50 | 0.77 | 0.23 |
CRHR 2 | 1.09 | 1.56 | 0.86 | 0.93 | 0.49 | 0.42 | 0.58 | 0.55 |
Adrenal | ||||||||
MC2R | 1.30 | 1.07 | 1.29 | 0.82 | 0.20 | 0.11 | 0.38 | 0.41 |