Table 1 Demographic and laboratory features of the patients with multiple sclerosis and healthy controls.

From: White blood cell count profiles in multiple sclerosis during attacks before the initiation of acute and chronic treatments

 

Patients with MS

HC

p value

n

64

2492

Male, n (%)

13 (20.3%)

638 (25.6%)

0.3376

Age*

34 (28–43) years

35 (32–38) years

0.4335

Current smoker, n (%)

11/61 (18.0%)

562/2485 (22.6%)

0.3971

Ex-smoker, n (%)

4/61 (6.6%)

554/2485 (22.3%)

0.0016

Body-mass index

21.8 (19.7–24.3)

21.4 (19.5–24.0)

0.4435

Total WBC count [/μL]*

6300 (5500–7400)

5400 (4500–6500)

< 0.0001

RBC count [× 106/μL]*

4.65 (4.43–4.86)

4.53 (4.29–4.83)

0.0260

Platelet count [× 103/μL]*

272 (238–304)

251 (217–289)

0.0155

Monocyte [/μL]*

315 (238–380)

258 (202–323)

< 0.0001

Lymphocyte [/μL]*

1810 (1480–2290)

1770 (1480–2130)

0.5025

Eosinophil [/μL]*

135 (80–240)

120 (70–200)

0.3523

Basophil [/μL]*

40 (20–50)

30 (20–40)

0.0027

Neutrophil [/μL]*

3740 (3000–4750)

3100 (2440–3980)

< 0.0001

PLR*

143 (113–186)

140 (114–174)

0.3142

MLR*

0.166 (0.142–0.201)

0.142 (0.113–0.180)

0.0003

NLR*

2.10 (1.49–3.24)

1.75 (1.37–2.23)

0.0029

  1. The p values were calculated using the chi-square test for sex ratio and current smoker ratio, Fisher’s exact test for ex-smoker ratio, and the Mann–Whitney U test for other variables. The total WBC, monocyte, basophil, and neutrophil counts were significantly higher in the MS group than in the HC group.
  2. HC, healthy control; MLR, monocyte-to-lymphocyte ratio; MS, multiple sclerosis; NLR, neutrophil-to-lymphocyte ratio; PLR, platelet-to-lymphocyte ratio; RBC, red blood cell; WBC, white blood cell count.
  3. *Median and interquartile range (25–75 percentiles).