Table 2 Correlation matrix between white blood cell subtypes in patients with MS and healthy controls.
Lymphocyte | Monocyte | Eosinophil | Basophil | Neutrophil | |
|---|---|---|---|---|---|
HC (n = 2492) | |||||
Lymphocyte | – | R = + 0.395* | R = + 0.257* | R = + 0.195* | R = + 0.329* |
Monocyte | (p < 0.0001) | – | R = + 0.241* | R = + 0.158* | R = + 0.535* |
Eosinophil | (p < 0.0001) | (p < 0.0001) | – | R = + 0.344* | R = + 0.153* |
Basophil | (p < 0.0001) | (p < 0.0001) | (p < 0.0001) | – | R = + 0.126* |
Neutrophil | (p < 0.0001) | (p < 0.0001) | (p < 0.0001) | (p < 0.0001) | – |
Patients with MS (n = 64) | |||||
Lymphocyte | – | R = + 0.099 | R = + 0.193 | R = + 0.467* | R = –0.096 |
Monocyte | (p = 0.4380) | – | R = + 0.117 | R = + 0.241 | R = + 0.412* |
Eosinophil | (p = 0.1260) | (p = 0.3585) | – | R = + 0.311 | R = + 0.162 |
Basophil | (p = 0.0001) | (p = 0.0553) | (p = 0.0125) | – | R = + 0.105 |
Neutrophil | (p = 0.4501) | (p = 0.0007) | (p = 0.2002) | (p = 0.4098) | – |
Difference in correlation coefficients between HC and MS groups | |||||
Lymphocyte | – | p = 0.0139 | p = 0.6039 | p = 0.0173 | p = 0.0007* |
Monocyte | (z = 2.461) | – | p = 0.3214 | p = 0.5055 | p = 0.2191 |
Eosinophil | (z = 0.519) | (z = 0.992) | – | p = 0.7721 | p = 0.9426 |
Basophil | (z = –2.380) | (z = –0.666) | (z = 0.290) | – | p = 0.8695 |
Neutrophil | (z = 3.382) | (z = 1.229) | (z = –0.072) | (z = 0.164) | – |
