Table 2 Histopathological grading scores.
From: Losartan improves intestinal mucositis induced by 5-fluorouracil in mice
Scores | Description of the findings |
|---|---|
0 | Histological findings are normal |
1 | Loss of crypt architecture and villus shortening, sparse inflammatory cell infiltration, presence of vacuolization and edema in the mucous layer and normal muscle layer |
2 | Villus blunting with flattened and vacuolated cells, crypt necrosis, moderate inflammatory cell infiltration, vacuolization and edema in the mucosal and submucosal layers and normal muscle layer |
3 | Villus blunting with flattened and vacuolated cells, crypt necrosis, intense inflammatory cell infiltration, vacuolization and edema in the mucosal and submucosal layers and muscle layer showing edema, vacuolization and neutrophilic infiltration |
