Table 3 Genotype and allele frequencies of MUC1 rs4072037 in ASSD-ILD+ and IPF patients.

From: Role of MUC1 rs4072037 polymorphism and serum KL-6 levels in patients with antisynthetase syndrome

 

ASSD-ILD+ % (n)

IPF% (n)

p

OR [95% CI]

p*

OR [95% CI]*

Genotypes

TT

19.5 (29)

32.7 (57)

Ref.

Ref.

TC

53.0 (79)

48.3 (84)

0.03

1.85 [1.07–3.18]

0.05

1.91 [0.99–3.68]

CC

27.5 (41)

19.0 (33)

0.006

2.44 [1.29–4.63]

0.007

2.84 [1.33–6.08]

Alleles

T

46.0 (137)

56.9 (198)

Ref.

Ref.

C

54.0 (161)

43.1 (150)

0.006

1.55 [1.14–2.12]

0.007

1.68 [1.16–2.44]

  1. ASSD: antisynthetase syndrome; CI: confidence interval; ILD: interstitial lung disease; IPF: idiopathic pulmonary fibrosis; OR: odds ratio. Statistically significant results are highlighted in bold.
  2. *Adjusted for age and sex.