Table 2 Impact of the drinking temperature, the number of drinks/day and of demographic factors (age, BMI) on induction of nuclear anomalies reflecting acute cytotoxicity and cell proliferation (basal cells) in buccal cells. p-values from Poisson regression.

From: Investigations concerning the impact of consumption of hot beverages on acute cytotoxic and genotoxic effects in oral mucosa cells

Endpoint

Predictor

OR

95% CI

p-value

p for trend

KR

Tea temperature < 55 °C

1 (Ref)

   

55–59 °C

0.99

0.81–1.20

0.916

 

60–64 °C

1.80

1.51–2.14

< 0.001

 

65–69 °C

2.33

1.95–2.78

< 0.001

 

70 + °C

2.75

2.40–3.16

< 0.001

< 0.001

 > 60 °C

2.20

2.01–2.42

0.000

 

Overweight (BMI 25–29.9)

1.04

0.94–1.16

0.409

 

Age (per decade)

1.00

0.95–1.06

0.888

 

# drinks/day

0.85

0.79–0.91

< 0.001

 

KL

Tea temperature < 55 °C

1 (Ref)

   

55–59 °C

0.95

0.82–1.10

0.477

 

60–64 °C

1.81

1.60–2.06

< 0.001

 

65–69 °C

2.40

2.11–2.74

< 0.001

 

70 + °C

3.86

3.50–4.26

< 0.001

< 0.001

> 60 °C

2.84

2.66–3.04

< 0.001

 

Overweight (BMI 25–29.9)

0.98

0.91–1.05

0.522

 

Age (per decade)

1.13

1.09–1.18

< 0.001

 

# drinks/day

0.94

0.89–0.99

0.014

 

CC

Tea temperature < 55 °C

1 (Ref)

   

55–59 °C

1.06

0.87–1.29

0.557

 

60–64 °C

1.25

1.04–1.50

0.018

 

65–69 °C

1.72

1.42–2.09

< 0.001

 

70 + °C

2.78

2.42–3.19

< 0.001

< 0.001

 > 60 °C

2.15

1.95–2.37

< 0.001

 

Overweight (BMI 25–29.9)

1.07

0.96–1.19

0.231

 

Age (per decade)

1.04

0.98–1.10

0.211

 

# drinks/day

1.02

0.94–1.10

0.637

 

PY

Tea temperature < 55 °C

1 (Ref)

   

55–59 °C

1.37

0.64–2.91

0.417

 

60–64 °C

1.83

0.89–3.74

0.098

 

65–69 °C

3.06

1.51–6.19

0.002

 

70 + °C

3.83

2.19–6.70

< 0.001

< 0.001

> 60 °C

2.71

1.86–3.93

< 0.001

 

Overweight (BMI 25–29.9)

1.00

0.67–1.48

0.991

 

Age (per decade)

0.98

0.79–1.23

0.882

 

# drinks/day

0.90

0.68–1.20

0.479

 

Basal

Tea temperature < 55 °C

1 (Ref)

   

55–59 °C

0.95

0.79–1.14

0.597

 

60–64 °C

1.12

0.94–1.33

0.219

 

65–69 °C

1.52

1.26–1.83

< 0.001

 

70 + °C

1.83

1.60–2.09

< 0.001

< 0.001

> 60 °C

1.51

1.37–1.66

< 0.001

 

Overweight (BMI 25–29.9)

0.96

0.86–1.07

0.459

 

Age (per decade)

1.05

0.99–1.11

0.121

 

# drinks/day

1.02

0.94–1.10

0.620

 
  1. KR Karyorrhexis, KL karyolysis, CC condensed chromatin, PY pyknosis, OR odds ratio, CI confidence interval.
  2. Number of participants per temperature group: < 55 °C (n = 21); 55–59 °C (n = 11); 60–64 °C (n = 15); 65–69 °C (n = 6); 70 + °C (n = 20).
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