Table 1 Linearity study summary.

From: A SARS-CoV-2 antigen rapid diagnostic test for resource limited settings

Viral copies/RDT

TCID50/mL

Test line result (+/−)

Control line result (+/−)

2.86 × 105

1.6 × 103

 + 

 + 

1.43 × 105

8.0 × 102

 + 

 + 

7.17 × 104

4.0 × 102

 + 

 + 

3.59 × 104

2.0 × 102

 + 

 + 

1.79 × 104

1.0 × 102

 − 

 + 

8.96 × 103

50

 − 

 + 

0

0

 − 

 + 

  1. The dilution in bold (3.59 x 104 viral copies/RDT, 2.0 x 102 TCID50/mL) was the lowest detectable dilution in the series.
  2. Visually interpreted test results of heat inactivated reference SARS-CoV-2 virus dilutions into pooled negative nasal swab sample (n = 2 per dilution). All samples with 1.79 × 104 viral copies or less per RDT cassette as well as the zero-virus negative control did not generate a visible test line and were interpreted as negative. All test cassettes have a visible red control line, indicating all tests were valid.
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