Table 3 The comparison of extent and severity of inflammation and fibrosis in pathology between the experimental and control groups.

From: Evaluation of the effect of filtered ultrafine particulate matter on bleomycin-induced lung fibrosis in a rat model using computed tomography, histopathologic analysis, and RNA sequencing

 

Experimental group

Control group

P-value

Inflammation extent, n (%)

   

none

0 (0%)

0 (0%)

 < 0.001

 < 25%

0 (0%)

9 (90%)

 

25–50%

3 (30%)

1 (10%)

 

 > 50%

7 (70%)

0 (0%)

 

Inflammation severity, n (%)

   

none

0 (0%)

0 (0%)

0.019

mild

5 (50%)

8 (80%)

 

moderate

5 (50%)

2 (20%)

 

severe

0 (0%)

0 (0%)

 

Pathologic inflammation score

4.80 ± 1.14

2.30 ± 0.48

 < 0.001

Fibrosis extent, n (%)

   

none

2 (20%)

5 (50%)

0.35

 < 25%

8 (80%)

5 (50%)

 

25–50%

0 (0%)

0 (0%)

 

 > 50%

0 (0%)

0 (0%)

 

Fibrosis severity, n (%)

   

none

2 (20%)

5 (50%)

0.067

mild

4 (40%)

5 (50%)

 

moderate

4 (40%)

0 (0%)

 

severe

0 (0%)

0 (0%)

 

Pathologic fibrosis score

2.00 ± 1.16

1.00 ± 1.05

0.042