Table 1 Baseline characteristics of participants, demographic and clinical history of the patients enrolled in the study.
Characteristics | Normal healthy controls (n/mean ± SD) | ALL patients (n/mean ± SD) | Follow up cases (n/mean ± SD) |
|---|---|---|---|
Total subjects (n = 110) | 24 | 66 | 20 |
Age | |||
Childhood | 14 | 42 | 15 |
Adult | 10 | 24 | 5 |
Gender | |||
Male (n) | 16 | 53 | 17 |
Female (n) | 8 | 13 | 3 |
Age (years) | 20.708 ± 13.788 (4.0–47.0) | 18.17 ± 11.29 (4.0–48.0) | 21.600 ± 6.6285 (5.0–43.0) |
Patients Characteristics | ALL (n) | B-ALL (n) | T-ALL (n) |
Type | 66 | 31 | 35 |
Age | |||
Childhood | 42 | 14 | 28 |
Adult | 24 | 17 | 07 |
Gender | |||
Male | 53 | 22 | 31 |
Female | 13 | 09 | 04 |
Risk | |||
High | 43 | 28 | 15 |
Standard | 23 | 03 | 20 |
Fever | |||
Yes | 62 | 28 | 34 |
No | 04 | 03 | 01 |
Weakness | |||
Yes | 40 | 20 | 20 |
No | 26 | 11 | 15 |
Weight loss | |||
Yes | 14 | 06 | 08 |
No | 52 | 25 | 27 |
Breathlessness | |||
Yes | 05 | 03 | 02 |
No | 61 | 28 | 33 |
Anorexia | |||
Yes | 12 | 05 | 07 |
No | 54 | 26 | 28 |
Pallor | |||
Yes | 54 | 23 | 31 |
No | 12 | 08 | 04 |
Body ache | |||
Yes | 41 | 20 | 21 |
No | 25 | 11 | 14 |
Cough | |||
Yes | 14 | 04 | 10 |
No | 52 | 27 | 25 |
Bleeding | |||
Yes | 18 | 06 | 12 |
No | 48 | 25 | 23 |
Epistaxis | |||
Yes | 06 | 01 | 05 |
No | 60 | 30 | 30 |
Bruising | |||
Yes | 02 | 00 | 02 |
No | 64 | 31 | 33 |
Petechia | |||
Yes | 05 | 01 | 04 |
No | 61 | 30 | 31 |
Vomiting/nausea | |||
Yes | 16 | 04 | 12 |
No | 50 | 27 | 23 |
Hepatomegaly | |||
Yes | 30 | 14 | 16 |
No | 36 | 17 | 19 |
Splenomegaly | |||
Yes | 44 | 21 | 23 |
No | 22 | 10 | 12 |
Lymphadenopathy | |||
Yes | 35 | 12 | 23 |
No | 31 | 19 | 12 |
BCR-ABL | |||
Negative | 60 | 25 | 35 |
Positive | 06 | 06 | 00 |
CNS infiltration | |||
Yes | 02 | 00 | 02 |
No | 64 | 31 | 33 |
Age (years) | 18.17 ± 11.29 (4.00–48.0) | 22.64 ± 13.74 (5.0–48.0) | 15.22 ± 6.68 (5.00–38.0) |
Height (cm) | 149.93 ± 27.68 (39.0–185) | 153.0 ± 21.74 (95.0–181) | 147.1 ± 32.10 (39.0–185) |
Weight (kg) | 49.04 ± 19.98 (13.0–100) | 52.22 ± 22.50 (16.0–100) | 46.22 ± 17.28 (13.0–78.0) |
Hemoglobin (g/dL) | 7.516 ± 2.12 (2.90–11.9) | 7.519 ± 2.03 (3.90–11.9) | 7.514 ± 2.22 (2.90–11.9) |
RBC’s (106/µL) | 2.931 ± 0.83 (1.4–5.40) | 2.907 ± 0.851 (1.44–5.38) | 2.952 ± 0.839 (1.53–5.40) |
WBC’s (109/L) | 48.93 ± 88.02 (1.40–480) | 25.31 ± 25.24 (1.40–89.7) | 69.85 ± 115.3 (2.90–480) |
Lymphocytes (%) | 77.36 ± 9.34 (43.5–89.9) | 75.53 ± 9.16 (56.4–88.6) | 78.98 ± 9.32 (43.5–89.9) |
Neutrophils (%) | 17.86 ± 8.67 (5.10–44.0) | 20.22 ± 8.99 (7.10–41.2) | 15.78 ± 7.92 (5.10–44.0) |
Platelets (109/L) | 45.22 ± 41.61 (1.70–224) | 49.24 ± 48.19 (7.00–224) | 41.66 ± 35.12 (1.70–154) |
PB blasts | 69.72 ± 23.29 (10.0–96.0) | 68.50 ± 23.84 (10.0–96.0) | 71.23 ± 22.81 (12.0–95.0) |
