Table 2 Plasma levels of mir-146a and hematological parameters before and after treatment in ALL.
Parameter | Normal (n = 24) | Pre-treatment (n = 20) | Post-treatment (n = 20) | P-value |
|---|---|---|---|---|
Hb (g/dL) | 13.50 ± 0.79 | 7.24 ± 2.19 | 11.32 ± 1.316 | < 0.0001 |
RBCs (106/µL) | 4.364 ± 0.51 | 2.917 ± 0.91 | 3.953 ± 0.44 | < 0.0001 |
HCT (%) | 41.31 ± 2.55 | 29.81 ± 14.60 | 35.09 ± 4.55 | < 0.0001 |
MCV (fl) | 86.95 ± 5.63 | 80.20 ± 13.28 | 86.75 ± 4.67 | 0.0143 |
MCH (pg) | 30.30 ± 2.67 | 23.87 ± 5.72 | 30.31 ± 2.62 | < 0.0001 |
MCHC (g/dL) | 33.63 ± 1.67 | 33.76 ± 7.46 | 34.08 ± 1.89 | 0.1738 |
WBCs (109/L) | 8.224 ± 1.87 | 45.51 ± 78.73 | 9.441 ± 5.51 | < 0.0001 |
Lymphocytes (%) | 31.08 ± 8.70 | 79.76 ± 9.83 | 27.71 ± 6.15 | < 0.0001 |
Neutrophils (%) | 50.3 ± 10.05 | 16.37 ± 8.24 | 50.65 ± 11.2 | < 0.0001 |
Mixed cells (%) | 18.62 ± 10.42 | 3.868 ± 2.68 | 21.79 ± 12.03 | < 0.0001 |
Platelets (109/L) | 299.7 ± 81.45 | 50.01 ± 35.9 | 289.2 ± 141.2 | < 0.0001 |
Plasma mir-146a (Fold change) | 1.365 ± 1.03 | 34.71 ± 15.26 | 0.9946 ± 0.83 | < 0.0001 |
