Table 3 Deaths, the median number of days of survival and odds ratio for fatty acids below or above level of skeletal muscle phospholipid fatty acids in cancer patients.

From: Depletion of essential fatty acids in muscle is associated with shorter survival of cancer patients undergoing surgery-preliminary report

 

Cut-point levela (ng/mg)

Below cut-point

Above cut-point

Cox regression analysis (categorical variable)

No. of patients, N

Event, N (%)

Survival time (median)

No. of patients, N

Event, N (%)

Survival time (median)

HR (95% CI)

p-value

Palmitoleic acid (16:1)

20.5

17

5 (29)

642

16

11 (69)

493

0.34 (0.11–0.99)

0.049

AA (20:4n-6)

136.9

19

12 (63)

478

14

4 (28)

742

3.45 (1.1–10.8)

0.033

EPA (20:5n-3)

7.2

20

13 (65)

480

13

3 (23)

719

4.39 (1.2–15.5)

0.022

DHA (22:6n-3)

25.2

21

13 (62)

477

12

3 (25)

806

4.30 (1.2–15.3)

0.024

  1. AA arachidonic acid, DGLA Dihomo-gamma-linolenic acid, DHA Docosahexaenoic acid, EPA Eicosapentaenoic acid.
  2. aCut-points were defined by optimum stratification. BMI, tumor site, metastasis and age were not significant predictors of number of days of survival.