Figure 2 | Scientific Reports

Figure 2

From: Selective activation of central thalamic fiber pathway facilitates behavioral performance in healthy non-human primates

Figure 2

Central thalamic deep brain stimulation (CT-DBS) of primary ascending arousal system pathway. (A) Post-operative localization of the three DBS leads in the right thalamus of NHP3, with axial (left) and coronal (right) views. The computed tomography artifact of the DBS lead contacts, see insets with individual contact, is fused with the macaque MRI atlas and overlaid with segmentations of the thalamic reticular nucleus (TRN) shown in purple, the central lateral (CL) nucleus in red, and the centromedian-parafascicularus complex (Cm-Pf) in magenta. (B) Reconstruction of the lead locations for the three NHP subjects in the sagittal (left), axial (middle), and coronal (right) planes, along with the thalamic nuclei in A and the two predominant fiber pathways: the medial Dorsal Tegmental Tract (DTTm) shown in blue and the Cm-Pf fibers in orange.

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