Figure 5
Effective stimulation configurations selectively activate thalamic pathways. (A) Combined lead locations of all three NHPs in one coronal image with the two predominant fiber pathways: the DTTm in blue and the Cm-Pf fibers in orange. (B) Stimulation configurations across all animals grouped by those that had a positive effect on performance (left), no effect (middle), and a negative effect (right) and the normalized percentage of how many configurations in that group activated the fibers in each pathway. 100% means that every configuration in the effect group activated that specific fiber, and 0% means that no configuration in that group activated that specific fiber. Nearly every stimulation configuration in the positive effect group activates nearly every fiber in the DTTm while activating minimal Cm-Pf fibers. The no effect group and the negative effect groups had reduced percentages of configuration activation of the DTTm and increasing activation of the Cm-Pf fibers.
