Table 3 Relationship of OCT-A metrics with average RNFL thickness in PACG, NTG, and Controls.

From: Comparison of optical coherence tomography angiography metrics in primary angle-closure glaucoma and normal-tension glaucoma

OCT-A metrics

 

Univariable model

Multivariable model

Average RNFL thickness, μm (95%CI)

P value

Average RNFL thickness, μm (95%CI)

P value

PACG

cpVD (%)

Per SD decrease

−5.855 (−9.567, −2.143)

0.002

−4.242 (−8.120, −0.363)

0.032

cpFD

Per SD decrease

−9.297 (−11.682, −6.913)

 < 0.001

−8.894 (−11.925, −5.864)

 < 0.001

NTG

cpVD (%)

Per SD decrease

−4.998 (−7.674, −2.322)

 < 0.001

−5.531 (−9.472, −1.590)

0.006

cpFD

Per SD decrease

−9.831 (−15.901, −3.761)

0.002

−12.064 (−17.195, −6.932)

 < 0.001

Controls

cpVD (%)

Per SD decrease

1.918 (−0.684, 4.520)

0.148

2.221 (−0.197, 4.638)

0.072

cpFD

Per SD decrease

−0.646 (−3.284, 1.992)

0.631

−1.325 (−3.891, 1.241)

0.312

  1. Significant values are in bold.
  2. cpVD = circumpapillary vessel density; cpFD = circumpapillary fractal dimension; PACG = primary angle closure glaucoma; NTG = normal tension glaucoma; RNFL = retinal nerve fiber layer; CI = confidence interval; SD = standard deviation. Multivariable model adjusted for age, sex, spherical equivalent, intraocular pressure, number of glaucoma medications and OCT-A image quality score.
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