Table 3 Associations of genetically predicted SHBG with ischemic heart disease in the UK Biobank using multivariable MR controlling for bioavailable testosterone in men.

From: Genetically predicted sex hormone binding globulin and ischemic heart disease in men and women: a univariable and multivariable Mendelian randomization study

Methods

OR

95% CI

p

MVMR Egger intercept p

MVMR IVW

0.79

0.71, 0.88

1.1 × 10–5

 

MVMR median

0.83

0.73, 0.95

0.005

 

MVMR Egger

0.83

0.72, 0.94

0.005

0.19

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