Figure 8 | Scientific Reports

Figure 8

From: Broad spectrum of CRISPR-induced edits in an embryonic lethal gene

Figure 8

Representation of T/brachyury allele sequences within each individual. Colored segments depict the fraction of each edited allele among all sequences for the respective sample; wildtype sequences are indicated by black color. The color scheme corresponds to the same deletion size classes as defined in Fig. 7. Size of each INDEL (as listed in Table 1) is given in the legend below each sample. Samples are ordered by the total number of alleles detected (edited and wildtype), with individuals harboring 2 alleles at the top, and those with the most alleles at the bottom of the figure. Within each allele class, samples are ordered from left to right according to descending proportion of the most prominent edited allele.

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