Figure 3 | Scientific Reports

Figure 3

From: PCBP1 regulates the transcription and alternative splicing of metastasis‑related genes and pathways in hepatocellular carcinoma

Figure 3

Analysis of binding characteristics of PCBP1. (A) Bar plot showing the reads distribution across different genomic regions. (B) Peak reads density in 5′UTR, CDS and 3′UTR. These three regions of each gene were separated into 100 bins, the PCBP1 peak reads in each bin was calculated. The reads density of PCBP1 peaks in all genes were plotted. (C) Venn diagram showing the overlapped peaks in two IP samples. (D) Bar plot showing the distribution of overlapped peaks across different genomic regions. (E) Motif analysis showing the top 3 preferred bound motifs of PCBP1 using HOMER software. (F) Bar plot exhibited the most enriched GO biological process results of PCBP1-bound genes. PCBP1, Poly C Binding Protein 1; UTR, untranslated region.

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