Figure 5 | Scientific Reports

Figure 5

From: PCBP1 regulates the transcription and alternative splicing of metastasis‑related genes and pathways in hepatocellular carcinoma

Figure 5

The expression level of PCBP1 in HCC tissues was lower than that in normal tissues, and the survival time of patients with low expression of PCBP1 was lower. (A) Based on liver hepatocellular carcinoma (HCC) data in TCGA database, the expression level of PCBP1 in HCC tissues was higher than that in normal tissues. (B) Quantitative experiments were carried out in 15 cases of HCC and 15 cases of normal liver tissues. The results showed that the expression level of PCBP1 in HCC tissues were lower than that in normal tissues, that is, the expression level of PCBP1 was downregulated. (C) Based on the data of HCC in TCGA database, the expression level of PCBP1 in different stages of HCC was analyzed. (D) Prognostic analysis of PCBP1 was performed using the kmplot online tool, and the results showed that the survival time of patients with low expression of PCBP1 was lower. PCBP1, Poly C Binding Protein 1; HCC, hepatocellular carcinoma; TCGA, the cancer genome atlas program.

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