Table 1 Clinical characteristics of the patients.

From: Influenza virus vaccination in pediatric nephrotic syndrome significantly reduces rate of relapse and influenza virus infection as assessed in a nationwide survey

 

All (N = 306)

Flu vaccination (N = 102)

No flu vaccination (N = 204)

p value

  Background; second questionnaire

  Age at onset of NS (years)

6.0 ± 4.1

5.6 ± 4.0

6.2 ± 4.2

0.26

  Boy: Girl, n (%)

215: 91 (70.3%: 29.7%)

76: 26 (74.5%: 25.5%)

139: 65 (68.1%: 31.9%)

0.25

  Gestational week*

38.7 ± 2.3

38.7 ± 2.2

38.7 ± 2.3

0.48

  Birth weight

2945 ± 497

2983 ± 507

2925 ± 491

0.71

  Family history of NS, n (%)

9 (3.0%)

1 (1.0%)

8 (4.0%)

0.28

  History of allergy, n (%) §

114 (38.4%)

44 (43.6%)

70 (35.7%)

0.19

    Asthma

36 (12.1%)

11 (10.9%)

25 (12.8%)

0.64

    Atopic dermatitis

34 (11.4%)

12 (11.9%)

22 (11.2%)

0.87

    Allergic rhinitis

56 (18.9%)

22 (21.8%)

34 (17.3%)

0.35

    Allergic conjunctivitis

8 (2.7%)

4 (4.0%)

4 (2.0%)

0.45

    Food allergy

28 (9.4%)

9 (8.9%)

19 (9.7%)

0.83

    Other

6 (2.0%)

2 (2.0%)

4 (2.0%)

1.0

  Hematuria at onset of NS, n (%) ||

95 (31.5%)

35 (35.0%)

60 (29.7%)

0.35

  Past history of frequent-relapsing NS, n (%)

147 (48.0%)

39 (38.2%)

108 (52.9%)

0.015

  Past history of steroid-dependent NS, n (%)

134 (43.8%)

38 (37.3%)

96 (47.1%)

0.1

  Past history of steroid-resistant NS, n (%)

29 (9.6%)

9 (8.9%)

20 (10.0%)

0.76

  Renal biopsy, n (%) **

163 (54.3%)

50 (50.0%)

113 (55.6%)

0.45

  Classification of renal histology

   

0.25

    Minimal change

132 (81.0%)

40 (80.0%)

92 (81.4%)

 

    Focal segmental glomerular sclerosis

14 (8.6%)

7 (14.0%)

7 (6.2%)

 

    Diffuse mesangial proliferation

9 (5.5%)

0 (0.0%)

9 (8.0%)

 

    Other

8 (4.9%)

3 (6.0%)

5 (4.4%)

 
  1. NS; nephrotic syndrome, Flu; influenza virus, FRNS; frequently relapsing NS, SDNS; steroid-dependent NS, SRNS; steroid-resistant NS.
  2. * Evaluated 246 children with data for gestational weeks. † Evaluated 254 children with data of birth weight. ‡ Evaluated 299 children with data for family history of SRNS. § Evaluated 297 children with data for history of allergy. || Evaluated 302 children with data for hematuria at onset of NS. ¶ Evaluated 301 children with data of past history of SRNS. ** Evaluated 300 children with data of renal biopsy.