Figure 7

Localisation and effect of SCPPPQ1 on P. gingivalis bacteria using TEM imaging. (a) TEM micrographs of pre-embedded immunogold preparations of bacteria from negative control (left) and + SCPPPQ1 treated (right) samples at 20 min. No or very few gold particles (black dots) are present in the negative control while particles are associated with the bacterial surface in + SCPPPQ1 samples. (b) TEM micrographs of bacteria sections from the negative control (left) and + SCPPPQ1 treated (right) samples at 20 min. Following treatment with + SCPPPQ1, alteration of bacterial membrane (arrows), bacterial debris (BD) and aggregated material (AM) can be visualized. Micrographs are representative from three different experiments.