Table 1 Analytic cohort characteristics by Day 0 procalcitonin levels.
Characteristic | Day 0 procalcitonin | Total | P-value | |
|---|---|---|---|---|
< 0.50 µg/L | ≥ 0.50 µg/L | |||
No | 180 | 239 | 419 | |
Age years Mean (SD) | 63.1 (15.5) | 65.4 (14.2) | 64.4 (14.8) | 0.11 |
Female No. (%) | 76 (42) | 73 (31) | 149 (36) | 0.013 |
SAPS II Mean (SD) | 32.3 (16.5) | 34.2 (14.5) | 33.4 (15.4) | 0.22 |
C-reactive protein Day 0 Mean (SD) | 87.0 (74.5) | 152.3 (90.8) | 124.2 (90.1) | < 0.001 |
Day 0 25(OH)D Mean (SD) | 14.6 (6.3) | 13.4 (10.4) | 13.9 (8.9) | 0.19 |
Vitamin D3 Intervention No. (%) | 79 (44) | 127 (53) | 205 (49) | 0.061 |
Change in 25(OH)D Day 0 to Day 3 Median [IQR] | 2.8 [− 0.4, 25.1] | 3.3 [0.1, 12.2] | 3.1 [0, 16.7] | 0.34 |
Total Bilirubin Day 0 Mean (SD) | 0.8 (0.9) | 2.1 (3.3) | 1.6 (2.6) | < 0.001 |
Creatinine Day 0 Mean (SD) | 1.0 (0.7) | 1.7 (1.1) | 1.4 (1.0) | < 0.001 |
ICU | < 0.001 | |||
Anesthesia ICU No. (%) | 27 (15) | 53 (22) | 80 (19) | |
Cardiac surgery ICU No. (%) | 27 (15) | 95 (40) | 122 (29) | |
Medical ICU No. (%) | 29 (16) | 60 (25) | 89 (21) | |
Neurological ICU No. (%) | 88 (49) | 18 (8) | 106 (25) | |
Surgical ICU No. (%) | 9 (5) | 13 (5) | 22 (5) | |
28-day mortality No. (%) | 25 (14) | 70 (29) | 95 (23) | < 0.001 |
