Table 1 Patients' demographics and clinicopathological characteristics.

From: Association between chemotherapy and prognostic factors of survival in hepatocellular carcinoma: a SEER population-based cohort study

Characteristics

Total

Non-chemotherapy

Chemotherapy

p value

SMD

(n = 1092)

(n = 546)

(n = 546)

Age at diagnosis, n (%)

   

0.425

0.079

 < 59 years

504 (46)

260 (47)

244 (45)

  

59–66 years

347 (32)

174 (32)

173 (32)

  

66–74 years

241 (22)

112 (21)

129 (23)

  

Sex, n (%)

   

0.882

0.013

Female

229 (21)

113 (21)

116 (21)

  

Male

863 (79)

433 (79)

430 (79)

  

Race, n (%)

   

0.972

0.014

White

736 (68)

369 (68)

367 (67)

  

Black

155 (14)

78 (14)

77 (14)

  

Other

201 (18)

99 (18)

102 (19)

  

AJCC, n (%)

   

0.675

0.075

I

426 (39)

207 (38)

219 (40)

  

II

389 (36)

204 (38)

185 (34)

  

III

185 (17)

89 (16)

96 (18)

  

IV

92 (8)

46 (8)

46 (8)

  

Grade, n (%)

   

0.823

0.058

Well differentiated

346 (32)

171 (31)

175 (32)

  

Moderately differentiated

551 (50)

272 (50)

279 (51)

  

Poorly differentiated

183 (17)

96 (18)

87 (16)

  

Undifferentiated

12 (1)

7 (1)

5 (1)

  

Tumor size, n (%)

   

0.889

0.029

 < 3.5 cm

504 (46)

255 (46)

249 (46)

  

3.5–7.2 cm

368 (34)

184 (34)

184 (33)

  

 > 7.2 cm

220 (20)

107 (20)

113 (21)

  

AFP, n (%)

   

0.429

0.052

Negative

331 (30)

159 (29)

172 (32)

  

Positive

761 (70)

387 (71)

374 (68)

  

Fibrosis score, n (%)

   

0.667

0.03

F0

253 (23)

130 (24)

123 (23)

  

F1

839 (77)

416 (76)

423 (77)

  

Radiotherapy, n (%)

   

1

0.006

No

993 (91)

496 (91)

497 (91)

  

Yes

99 (9)

50 (9)

49 (9)

  

Surgery, n (%)

   

0.914

0.044

No surgery

444 (41)

219 (40)

225 (41)

  

Hepatectomy

213 (20)

108 (20)

105 (19)

  

Hepatectomy and transplant

298 (27)

153 (28)

145 (27)

  

Others

137 (12)

66 (12)

71 (13)

  

Survival times, Median (IQR)

23.00 (11.00, 45.00)

22 (7.00, 46.75)

23.00 (13.00, 43.00)

0.017*

 
  1. *Two-sided P values < 0.05.
  2. **Two-sided P values < 0.01.
  3. ***Two-sided P values < 0.001.
  4. AJCC, American Joint Committee on Cancer (7th).
  5. F0, fibrosis score 0–4, non to moderate fibrosis; F1, fibrosis score 5–6, severe fibrosis and cirrhosis.
  6. IQR, Inter-Quartile Range.