Table 2 Incidences and hazard ratios associated with pulse pressure quartile for progression of chronic kidney disease.

From: Association between pulse pressure and progression of chronic kidney disease

 

Incident rate (per 1000 person-years)

Crude HR (95% CI)

p-value

Adjusted HR

p-value

Progression of CKD

PP (per 10 mmHg)

1.30 (1.20–1.42)

< 0.001

1.17 (1.06–1.29)

0.002

PP quartile

Q1 (≤ 48)

31.9 (44/1379)

1.00 (reference)

< 0.001*

1.00 (reference)

0.003*

Q2 (49–56)

40.5 (54/1333)

1.14 (0.85–1.89)

1.14 (0.74–1.76)

Q3 (57–65)

47.2 (55/1166)

1.47 (0.99–2.18)

1.35 (0.88–2.06)

Q4 (≥ 66)

90.1 (88/977)

2.72 (1.89–3.91)

1.87 (1.23–2.83)

  1. PP Pulse Pressure, CKD Chronic kidney disease, HR Hazard ratio, CI confidence interval. Adjusted HRs were obtained, controlling for age, sex, BP-lowering medication, diabetes, dyslipidemia, hyperuricemia, obesity, smoking, drinking, and baseline eGFR and proteinuria.
  2. *p for trend.