Figure 1

(A) Changes of mean (± SD) endotoxin activity levels with (black) and without (gray) PMX-HP treatment. (B) Probability of in-hospital death according to EA level at T0 categorized by treatment strategy. Dashed lines enclose the 95% CI. *p < 0.05 vs. baseline (T0); **p < 0.01 vs. baseline (T0); ***p < 0.001 vs. baseline (T0). EA endotoxin activity, PMX-HP polymyxin B-hemoperfusion, SD standard deviation.