Figure 5 | Scientific Reports

Figure 5

From: Intramammary treatment using allogeneic pure platelet-rich plasma in cows with subclinical mastitis caused by Gram-positive bacteria

Figure 5

Graphical representation of the risk difference for bacteriological cure between 10 mL of P-PRP (pure platelet rich plasma) and 75 mg of CS (cefquinome sulfate) over three consecutive milkings. The black dotted vertical line represents the non-inferiority margin (Δ), and the area to the right of this value (− 0.175) indicates the zone of non-inferiority. The solid square is the point-estimate of difference in cure between P-PRP and CS; caps of the horizontal lines indicate 95% CI. All cases = bacteriological cure of all cases, the CI does not span both zero and the non-inferiority margin (− Δ), which indicates that CS is significantly better. Streptococcus spp. (includes only Streptococcus uberis, Streptococcus agalactiae and Streptococcus dysgalactiae) = bacteriological cure in Streptococcus spp. cases: the CI spans − Δ but not 0, implying that CS is better, however, non-inferiority is inconclusive. Staph. aureus = bacteriological cure in Staphylococcus aureus cases: the CI does not span both − Δ and zero, thus CS is significantly better.

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