Figure 7
Modulation of global epidermal 3D melanin density with skin color ITA grade in constitutive pigmentation study. (a) Raw 2PEF intensity images (cyan hot) and Pseudo-FLIM melanin masks (purple) acquired within the basal layer of human forearm skin. High signal intensities appear in white color. (b) Modulation of 3D epidermal melanin density with ITA group and (c) with both ITA group and skin ethnicity. The data are expressed as boxplots with fences. (d) Correlation matrix of the skin colorimetric parameters and multiphoton melanin density estimated in the epidermis and its sub-layers. The data correspond to the Pearson correlation coefficients. An absolute value of the Pearson correlation coefficients between [0.6, 0.8] and [0.8, 1.0] indicate a strong and respectively a very strong correlation. ED (global epidermis), SC - stratum corneum, SC Disj - stratum corneum disjunctum, SC Comp - stratum corneum compactum, LED – living epidermis, SGranu - stratum granulosum, SSpin – stratum spinosum and SBas - stratum basale.
