Figure 6 | Scientific Reports

Figure 6

From: miR1908-5p regulates energy homeostasis in hepatocyte models

Figure 6

miR1908-5p mimic transfection reduces AMPK activity, LKB1 levels and ACC phosphorylation in HuH-7 cells. HuH-7 cells were treated for 72 h with either mimic inhibitor or miR1908 mimic, and their matching controls. Three distinct gels were probed; Ponceau of the 50 kDa region as loading control is shown. Quantification (average ± S.D from 3 biologics) is expressed relative to unphosphorylated (AMPK, ACC1) or TUBB (LKB1) and normalized internally to the matching control value MIM or INH vs matching ctl: *p < 0.05; **p < 0.01;***p < 0.001.

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