Figure 5 | Scientific Reports

Figure 5

From: Inference of tissue relative proportions of the breast epithelial cell types luminal progenitor, basal, and luminal mature

Figure 5

Linear modelling (with 95% C.I.s indicated) of estimated proportions of (a) luminal progenitor-like, (b) mature luminal-like, (c) basal-like, and (d) overall epithelial-like cells, in \(n=257\) tumour biopsies. The horizontal bars arranged along the vertical axis in each plot represent linear model predictors as follows: FA-gene (non-BRCA, FANC suffix) mutation carrier status, disease stage, and volunteer age. (e) Biopsies of FA-gene mutation carriers are mostly hormone receptor (HR) triple-negative, whereas those of (f) FA-gene wild-type are mostly HR-positive. Inferences are based on DNAme data.

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