Figure 4 | Scientific Reports

Figure 4

From: Immunoreactivity of the SARS-CoV-2 entry proteins ACE-2 and TMPRSS-2 in murine models of hormonal manipulation, ageing, and cardiac injury

Figure 4

ACE-2 and TMPRSS-2 immunoreactivity in lung alveoli in murine models of pregnancy. The violin plots (A and B) provide information on the full data distribution. The horizontal black line indicates the median of the kernel density plot. (A) ACE-2 immunoreactivity in lung alveoli of 12 months-old multiparous and nulliparous mice. (B) TMPRSS-2 immunoreactivity in lung alveoli of 12 months-old multiparous and nulliparous mice. (C) Serum progesterone level in both groups. Mann–Whitney test was performed to compare the median of the tissue expression of ACE-2 and TMPRSS-2 between nulliparous and multiparous. Unpaired Student’s t-test was applied for comparison of progesterone levels. Only significant p-values are reported (more details in Table 3). ACE-2, angiotensin-converting enzyme 2; TMPRSS-2, transmembrane protease serine 2.

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